first of all

英 [fɜːst ɒv ɔːl]

美 [fɜːrst əv ɔːl]

第一;首先

牛津词典

firstly在英国英语中比在北美英语中更通用。
Firstly is more common in BrE than in NAmE .
1. The brochure is divided into two sections, dealing firstly with basic courses and secondly with advanced ones.
  小册子分为两部分：第一部分涉及基础课程，第二部分涉及高级课程。
at first用以讲述最初阶段的情况，尤指与后来的不同情况相比较：
At first is used to talk about the situation at the beginning of a period of time, especially when you are comparing it with a different situation at a later period.
1. Maggie had seen him nearly every day at first. Now she saw him much less.
  起初玛吉几乎每天都见到他，现在见到他的次数少得多了。

adv

before anything else
1. first we must consider the garter snake
Synonym:firstfirstlyforemostfirst off

First of all, this paper described the definition and the security model of the identity-based encryption.
首先叙述了基于身份的加密定义和安全模型；
First of all, study how he is with other girls.
首先，研究一下他和其他女孩在一起是怎么样的。
First of all, we need more research on biofuels.
首先，我们需要对生物燃料进行更多的研究。
First of all, I think we should be kind to our students.
首先，我认为，我们应该和蔼地对待我们的学生。
First of all, this paper introduces a semantic component model and also makes extension to it.
首先，本文介绍了一种语义构件模型，并对其进行了扩展。
First of all, I like the zoo.
首先，我喜欢动物园。
First of all, could I begin with an apology for a mistake I made last week?
首先，请允许我为上周犯下的错误道歉。
First of all, I wanted to shake hands, all right?
首先我想和你握手言和好吗？
When you get there, first of all familiarize yourself with the situation.
你到了那里，要先熟悉当地的情况。
First of all, I have a passion, I will be happy to work.
首先，我有热情，我会快乐地投入工作。